Diploid genome reconstruction of Ciona intestinalis and comparative analysis with Ciona savignyi
نویسندگان
چکیده
منابع مشابه
Diploid genome reconstruction of Ciona intestinalis and comparative analysis with Ciona savignyi.
One of the main goals in genome sequencing projects is to determine a haploid consensus sequence even when clone libraries are constructed from homologous chromosomes. However, it has been noticed that haplotypes can be inferred from genome assemblies by investigating phase conservation in sequenced reads. In this study, we seek to infer haplotypes, a diploid consensus sequence, from the genome...
متن کاملUsing a custom Ciona intestinalis genome browser to visualize genomic conservation with Ciona savignyi
We have successfully designed a custom genome browser for visualization of the genome of the invertebrate chordate Ciona intestinalis. We describe the use of the genome browser to visualize the conservation between Ciona intestinalis and a related species, Ciona savignyi. Visualizing genomic conservation between these two organisms is important for determining genes and regulatory regions that ...
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1. Ciona possesses two means of responding to an increase in the intensity of illumination. One is by means of a local reaction; the other is by a retraction reflex of the body as a whole. 2. The "ocelli" are not photoreceptors. The photosensitive area is in the intersiphonal region containing the neural mass. This area contains no pigment. 3. The reaction time to light is composed of a sensiti...
متن کاملAssembly of polymorphic genomes: algorithms and application to Ciona savignyi.
Whole-genome assembly is now used routinely to obtain high-quality draft sequence for the genomes of species with low levels of polymorphism. However, genome assembly remains extremely challenging for highly polymorphic species. The difficulty arises because two divergent haplotypes are sequenced together, making it difficult to distinguish alleles at the same locus from paralogs at different l...
متن کاملNon-coding RNAs in Ciona intestinalis
MOTIVATION The analysis of animal genomes showed that only a minute part of their DNA codes for proteins. Recent experimental results agree, however, that a large fraction of these genomes are transcribed and hence are probably functional at the RNA level. A computational survey of vertebrate genomes has predicted thousands of previously unknown ncRNAs with evolutionarily conserved secondary st...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2007
ISSN: 1088-9051
DOI: 10.1101/gr.5894107